Extra or Missing Chromosomes
1 - 10 of 15 Answers
December 5, 2017:
I'm doing research for a book and I have a question regarding sex and gender. One of the biggest issues facing the LGBTQ today is transgender discrimination. Many people of course are arguing there are only just two genders (i.e. sexes) male and female. But in doing research, there seem to be more combinations at least at the DNA level. Instead of just XX and XY, there can be XXX, XXY, and X and many others besides.
Does this have to do with being transgender? From a genetic perspective, are there more sexes than male and female, or is everything else just classified as a disorder?
June 4, 2014:
How do you calculate the risks of having a child with Trisomy 21 if the mother is 44 years old, the father is 46 years old and there has already been one miscarriage due to Trisomy 21?
July 25, 2012:
If I marry someone with a history of Down’s syndrome in the family, will my kids be affected?
March 8, 2011: My nephew was born with an extra chromosome. He never developed past the stage of a two-month old, could only drink formula, and he lived until he was two years old. Is this genetic, and is there a name for it?
January 30, 2009: Are you born with the Philadelphia chromosome? If not, how do you get it?
January 22, 2009: My son was born with full trisomy 13. Is it possible to say how early the chromosome split the wrong way? In other words, was it before conception or very soon after? Or is it impossible to know? Thank you.
January 15, 2009:
My father is XYY. Is there something genetic that could have caused this when his father and mother conceived him? Or is this a totally random occurrence? Does him being XYY affect his offspring in anyway? If so how and why? Could it be possible it made him more likely to have girls?
July 23, 2008:
What could possibly cause a chromosome disorder like trisomy 18? I understand how it happens, but are there environmental factors that can cause the presence of an extra chromosome?
October 4, 2007: Why is it that older women are more likely to have babies with complications like Down syndrome than younger women?
July 19, 2007:
I have heard that the MTHFR mutation can affect whether a woman has a baby with Down syndrome or not. I have also heard that taking folic acid can help. Does the MTHFR mutation also affect men? Can they benefit from extra folic acid as well?
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